Why does chronic iron deficiency lead to impaired temperature regulation, causing increased susceptibility to hypothermia?

💡 Explanation

Iron deficiency impairs the heme synthesis needed for thyroid peroxidase, which is essential for converting T4 to T3, reducing overall thyroid hormone production because this conversion is compromised by decreased iron availability; therefore, less heat is generated, rather than through direct impairment of thermogenesis or vasoconstriction.

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