Why does drug X, administered intravenously, exhibit a longer half-life in a patient with chronic kidney disease compared to a healthy individual?

💡 Explanation

The half-life of a drug is prolonged when its elimination is impaired. Reduced renal clearance rate due to kidney disease means the drug is removed from the body slower, because the kidneys are less efficient at filtering the drug. Therefore, the half-life is extended rather than shortened by increased filtration.

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