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← Human Body & HealthWhy does Hashimoto's thyroiditis, an autoimmune condition, develop when thyroid follicular cells resemble certain pathogens?
A)Increased MHC I antigen presentation
B)Overactive cytotoxic T cell response
C)Regulatory T cell dysfunction✓
D)Elevated thyroid hormone production
💡 Explanation
Hashimoto's thyroiditis occurs due to molecular mimicry where the immune system attacks thyroid cells mistaken for pathogens. This happens because regulatory T cell function is impaired, leading to a breakdown in self-tolerance. Therefore, the immune system attacks the thyroid, rather than remaining suppressed by regulatory cells.
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