Why does hypothyroidism often persist in patients with sufficient iodine intake after thyroidectomy, despite TSH stimulation?

💡 Explanation

Hypothyroidism persists post-thyroidectomy because the reduced thyroid tissue mass cannot produce enough T3 and T4 to meet bodily demands, regardless of sufficient iodine intake and TSH stimulation. This insufficient capacity directly limits hormone synthesis; therefore, hormone levels remain low, rather than other compensatory mechanisms overcoming tissue loss.

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