Why does monospermy occur in humans after fertilization?

💡 Explanation

Monospermy occurs due to the cortical reaction; when a sperm fuses with the oocyte, cortical granules release enzymes that alter the zona pellucida and oocyte membrane, preventing other sperm from binding. This is because the oocyte activates the block to polyspermy mechanism, therefore ensuring diploidy, rather than allowing multiple fertilizations.

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