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Human Body & Health

Why does ovulation typically cease during the luteal phase after successful fertilization?

A)Decreased FSH receptor sensitivity
B)Increased prostaglandin synthesis locally
C)Negative feedback of progesterone on GnRH
D)Elevated inhibin suppresses pituitary action

💡 Explanation

Ovulation ceases during the luteal phase because progesterone, secreted by the corpus luteum after fertilization, exerts a negative feedback on the hypothalamus, which reduces the secretion of GnRH. This reduction suppresses FSH and LH release, thereby preventing further follicular development and ovulation, rather than just local prostaglandin effects; therefore, C is correct.

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