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← Human Body & HealthWhy does post-inflammatory hyperpigmentation (PIH) persist longer in individuals with darker skin tones after cutaneous wound healing?
A)Decreased melanocyte sensitivity to inflammation
B)Elevated fibroblast collagen production inhibition
C)Increased melanin transfer to keratinocytes✓
D)Reduced melanin degradation enzyme activity
💡 Explanation
PIH persists longer in darker skin because of increased melanin transfer via melanocytes to surrounding keratinocytes through melanosomes during inflammation; therefore, more melanin is deposited into the skin, making hyperpigmentation more pronounced, rather than melanocyte sensitivity decreasing or collagen production being directly inhibited.
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