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Human Body & Health

Why does post-inflammatory hyperpigmentation (PIH) persist longer in individuals with darker skin tones after cutaneous wound healing?

A)Decreased melanocyte sensitivity to inflammation
B)Elevated fibroblast collagen production inhibition
C)Increased melanin transfer to keratinocytes
D)Reduced melanin degradation enzyme activity

💡 Explanation

PIH persists longer in darker skin because of increased melanin transfer via melanocytes to surrounding keratinocytes through melanosomes during inflammation; therefore, more melanin is deposited into the skin, making hyperpigmentation more pronounced, rather than melanocyte sensitivity decreasing or collagen production being directly inhibited.

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