Why does reduced GnRH pulse frequency impair fertility in females undergoing assisted reproductive technology (ART)?

💡 Explanation

A reduced GnRH pulse frequency leads to a lower FSH:LH ratio because it alters the responsiveness of gonadotroph cells. This imbalance impairs proper follicle maturation, therefore reducing fertility in ART. This is because the follicle requires a specific FSH:LH balance rather than the other listed outcomes.

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