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← Human Body & HealthWhy does renal tubule obstruction caused by kidney stones containing calcium oxalate crystals typically lead to hydronephrosis?
A)Decreased glomerular filtration rate
B)Increased renin-angiotensin activation
C)Compensatory erythropoietin overproduction
D)Backpressure causing renal pelvic dilation✓
💡 Explanation
Hydronephrosis results from the buildup of urine in the kidney because the obstruction prevents normal outflow. The increased pressure from the retained urine causes dilation of the renal pelvis. Therefore, renal pelvic dilation is the correct answer, rather than decreased filtration, hormonal changes, or erythropoietin production.
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