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← Human Body & HealthWhy does thickened mucus in the alveoli of cystic fibrosis patients impair gas exchange more than reduced lung elasticity?
A)Lowered cardiac output compensation limits
B)Reduced diffusion gradient for gases✓
C)Increased alveolar surface tension excess
D)Enhanced alveolar macrophage recruitment
💡 Explanation
Thickened mucus directly impedes the diffusion of oxygen and carbon dioxide across the alveolar membrane because it increases the diffusion distance and reduces the concentration gradient. Therefore, gas exchange is severely compromised. Reduced elasticity affects ventilation, rather than the efficiency of diffusion at the alveolar surface.
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