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← Human Body & HealthA patient taking warfarin undergoes a liver function test. Which outcome affecting blood coagulation is most likely if liver function is severely impaired?
A)Increased antithrombin III production
B)Reduced synthesis of clotting factors✓
C)Elevated platelet aggregation activity
D)Enhanced fibrinolysis through plasminogen
💡 Explanation
Warfarin inhibits vitamin K epoxide reductase, which is vital for producing functional clotting factors in the liver. Because impaired liver function diminishes the production of these essential factors involved in the coagulation cascade, it leads to reduced blood clotting, therefore a reduced synthesis of clotting factors is the most likely outcome, rather than the other options which would increase clotting activity or are unrelated.
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