In a neuron affected by multiple sclerosis, what causes slower action potential propagation along the axon?

💡 Explanation

Multiple sclerosis involves the destruction of myelin sheaths, and because myelin facilitates saltatory conduction by insulating the axon and allowing action potentials to jump between nodes of Ranvier, demyelination disrupts this process, therefore slowing action potential propagation rather than altering ion channel kinetics or neurotransmitter dynamics.

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