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← Human Body & HealthA patient with hypertension has increased arterial stiffness and reduced baroreceptor sensitivity. If the RAAS system is chronically overactive, which outcome is most likely?
A)Decreased sodium reabsorption in kidney
B)Reduced plasma angiotensinogen levels
C)Elevated aldosterone secretion and volume✓
D)Increased renal potassium excretion only
💡 Explanation
Overactive RAAS will cause elevated aldosterone secretion because angiotensin II stimulates aldosterone release from the adrenal cortex, leading to increased sodium and water reabsorption and expansion of fluid volume. Therefore, hypertension worsens, rather than decreasing sodium reabsorption or directly influencing angiotensinogen levels.
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