A patient with severe anemia requires multiple blood transfusions. Which consequence is most likely due to decreased levels of 2,3-BPG in stored blood affecting hemoglobin?

💡 Explanation

Decreased 2,3-BPG in stored blood increases hemoglobin's oxygen affinity, because 2,3-BPG normally reduces affinity, promoting oxygen release. Therefore, less oxygen is delivered to tissues; rather than enhanced CO2 transport or improved pH buffering, which are independent processes.

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