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Human Body & Health

In liver cirrhosis, which consequence follows from increased intrahepatic resistance to blood flow caused by fibrosis and nodule formation?

A)Enhanced urea cycle activity
B)Increased bile acid synthesis
C)Decreased hepatic glucose output
D)Development of esophageal varices

💡 Explanation

Portal hypertension develops because fibrosis increases intrahepatic resistance, causing blood to back up into the portal system. Therefore, esophageal varices form as a consequence of this elevated pressure, rather than enhanced urea cycle, increased bile synthesis, or decreased hepatic glucose output.

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