A patient with type O negative blood requires an emergency transfusion after a severe car accident. Which consequence follows from mistakenly administering type B positive blood?

💡 Explanation

An acute hemolytic transfusion reaction arises because pre-existing anti-B and anti-Rh antibodies in the recipient's blood immediately bind to the transfused type B positive erythrocytes, causing complement activation and red blood cell lysis. Therefore, a severe, potentially fatal immune response occurs rather than iron overload, erythroblastosis (which requires prior sensitization), or protective vasodilation.

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