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Human Body & Health

An elderly patient contracts influenza; high viral load overwhelms the initial interferon response. Which consequence follows regarding adaptive immunity?

A)Accelerated antibody class switching occurs
B)Delayed T-cell activation and clearance
C)Hyperactive complement-mediated cytotoxicity
D)Uncontrolled macrophage activation occurs

💡 Explanation

A high viral load causing overwhelming interferon response delays T-cell activation and clearance because antigen presentation to T-cells becomes inefficient. This inefficiency is due to resource competition, therefore T-cell mediated clearance is delayed, rather than accelerated antibody production or complement hyperactivity, which depend on initial T-cell help.

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