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Human Body & Health

If a patient's thyroid gland contains adequate iodine but the peripheral tissues show decreased T3 production, which consequence follows?

A)Increased thyroid peroxidase activity
B)Decreased deiodinase enzyme activity
C)Elevated thyroglobulin synthesis rate
D)Reduced thyroid hormone receptor expression

💡 Explanation

Decreased T3 production in peripheral tissues despite sufficient iodine suggests impaired deiodinase enzyme activity, because these enzymes are responsible for converting T4 to the more active T3. Therefore, reduced activity leads to lower T3, rather than changes in the thyroid gland or receptor expression.

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