An individual with iodine deficiency consumes excessive amounts of cruciferous vegetables which further inhibits thyroid peroxidase. Which consequence is most likely regarding thyroid hormone regulation?

💡 Explanation

Iodine deficiency impairs thyroid hormone synthesis, and cruciferous vegetables contain goitrogens that inhibit thyroid peroxidase, crucial for iodination. Because of this combined inhibition, the body attempts to compensate via increased TSH secretion to stimulate the thyroid, therefore TSH will rise, rather than a suppression or direct alteration of T3/T4 levels.

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