An individual with iodine deficiency consumes kelp supplements; which consequence relating to thyroid hormone regulation is most probable initially?

💡 Explanation

Because iodine supplementation increases substrate availability for thyroid hormone synthesis, increased T4 production leads to greater T3 conversion by deiodinases in peripheral tissues. Initially, this may transiently suppress deiodinase activity through negative feedback mechanisms, therefore suppressing deiodinase activity is likely, rather than immediate TSH reduction, halting TRH release or rapidly accelerating T4 beyond regulatory capacity.

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