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Human Body & Health

Following chronic hepatitis, which outcome occurs when activated hepatic stellate cells increase extracellular matrix protein deposition beyond degradation capacity in the liver?

A)Increased bile acid synthesis
B)Enhanced glycogen storage capacity
C)Improved hepatic urea cycle
D)Development of liver cirrhosis

💡 Explanation

Liver cirrhosis develops because activated hepatic stellate cells deposit excessive extracellular matrix proteins, exceeding the degradation capacity, which then leads to fibrosis. Therefore, cirrhosis is the likely outcome, rather than changes in bile acid synthesis, glycogen storage, or urea cycle efficiency.

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