If a drug inhibits mTOR signaling specifically in skeletal muscle during resistance exercise, which consequence follows regarding muscle aging?

💡 Explanation

mTOR signaling promotes muscle hypertrophy; therefore, its inhibition reduces muscle size with aging, which ironically mitigates sarcopenia's effect. Inhibiting mTOR slows down the rate of protein synthesis and cell proliferation, because it reduces the cell's metabolic activity rather than increasing it.

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