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Life Sciences & Medicine

If a novel virus enters the body, which consequence follows from the activation of naïve B lymphocytes?

A)Immediate antibody-mediated virus neutralization
B)Decreased presentation via MHC class II
C)Clonal expansion and antibody production
D)Direct cytotoxic killing of infected cells

💡 Explanation

Naïve B lymphocytes, upon encountering their specific antigen, undergo clonal expansion and differentiate into antibody-secreting plasma cells; because this generates a large population of specific antibodies. Therefore, antibody production increases, rather than direct killing or immediate neutralization, which require prior sensitization.

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