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Human Body & Health

If a patient has a dysfunctional factor VIII, which consequence follows regarding blood coagulation?

A)Accelerated thrombin production occurs
B)Fibrin clot formation is impaired
C)Platelet aggregation increases rapidly
D)Prothrombin activation accelerates greatly

💡 Explanation

When factor VIII is dysfunctional, the intrinsic coagulation pathway is disrupted, because it cannot effectively activate factor X; therefore, fibrin clot formation is impaired, rather than other coagulation steps being accelerated, since they rely on the factor VIII contribution.

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