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← Human Body & HealthIf a patient has a dysfunctional factor VIII, which consequence follows regarding blood coagulation?
A)Accelerated thrombin production occurs
B)Fibrin clot formation is impaired✓
C)Platelet aggregation increases rapidly
D)Prothrombin activation accelerates greatly
💡 Explanation
When factor VIII is dysfunctional, the intrinsic coagulation pathway is disrupted, because it cannot effectively activate factor X; therefore, fibrin clot formation is impaired, rather than other coagulation steps being accelerated, since they rely on the factor VIII contribution.
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