If a patient's adaptive immune system produces antibodies that bind to and block the PD-1 receptor on T-cells, which consequence follows regarding immune responses to cancer cells?

💡 Explanation

Blocking PD-1 with antibodies prevents its interaction with PD-L1 on cancer cells. This interaction normally inhibits T-cell activation; therefore, blocking PD-1 unleashes T-cell mediated cytotoxicity against cancer cells, rather than diminishing it. Cancer cell MHC-I expression or antigen presentation efficiency are not directly affected by this mechanism.

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