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Human Body & Health

If a patient with a known bee sting allergy is exposed and experiences rapidly declining blood pressure, which consequence results from widespread mast cell degranulation?

A)Increased oxygen-hemoglobin affinity
B)Enhanced B-cell antibody production
C)Suppressed T-helper cell activation
D)Systemic vasodilation and capillary leakage

💡 Explanation

Widespread mast cell degranulation releases histamine and other mediators, causing systemic vasodilation and increased capillary permeability, because these factors dramatically lower blood pressure. Therefore, vasodilation and leakage are the immediate consequences, rather than altered oxygen affinity or immune cell modulation under acute anaphylaxis.

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