If a patient with diabetes insipidus does not have access to water for an extended period, which consequence follows due to the compromised regulation of water reabsorption?

💡 Explanation

Diabetes insipidus impairs ADH function, compromising water reabsorption in the collecting ducts; because water cannot be reabsorbed effectively, dehydration ensues, and cells lose water to the hypertonic extracellular fluid. Therefore, severe cellular dehydration occurs rather than decreased osmolality or altered electrolyte balance, which might occur under different conditions.

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