If an astronaut experiences symptoms of scurvy during a long-duration space mission, which consequence follows regarding collagen synthesis?

💡 Explanation

Vitamin C is crucial for the enzyme prolyl hydroxylase, which hydroxylates proline in collagen. Without this hydroxylation, procollagen's triple helix cannot properly form or stabilize, because hydrogen bonding is impaired; therefore, the stability of procollagen is compromised rather than enhanced.

• If a long-distance runner experiences a sharp decline in performance despite maintaining pace, which consequence related to intramuscular lactate accumulation is most likely?
• If a hiker ascends to high altitude, experiencing hypothermia despite wearing insulated clothing, which mechanism explains why core body temperature continues to drop despite maximal shivering?
• Following intramuscular injection of a novel subunit vaccine containing a TLR4 agonist adjuvant, which immunological outcome is most likely, compared to the same vaccine without adjuvant?
• Why does endurance performance diminish when an athlete limits water intake despite increased plasma osmolality?
• Why does thyroxine (T4) conversion to triiodothyronine (T3) decrease during prolonged starvation?
• An individual with iodine deficiency consumes excess cruciferous vegetables (e.g., broccoli, cabbage). Which consequence follows from the increased intake of glucosinolates?