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← Human Body & HealthIf a researcher isolates skeletal muscle fibers and introduces a non-hydrolyzable ATP analog during a contraction experiment, which consequence follows?
A)Increased calcium release from sarcoplasmic
B)Accelerated cross-bridge detachment rate
C)Persistent rigor state muscle contraction✓
D)Enhanced troponin-tropomyosin binding affinity
💡 Explanation
A non-hydrolyzable ATP analog prevents the myosin head from detaching from actin after the power stroke because ATP hydrolysis is required for this detachment. Therefore, a persistent rigor state results, rather than detachment, because the cycle is interrupted.
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