If ibuprofen is administered to inhibit COX enzymes during inflammation, which consequence affecting pain signaling pathways is most likely?

💡 Explanation

Ibuprofen inhibits cyclooxygenase (COX) enzymes, which reduces prostaglandin production. Because prostaglandins sensitize pain receptors, inhibiting their synthesis decreases pain signaling along the pathways. Therefore, prostaglandin synthesis decreases, rather than bradykinin or histamine effects increasing, or substance P increasing.

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