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Human Body & Health

If intense, prolonged exercise leads to increased oxidative stress within muscle fibers, which consequence most likely hinders long-term muscle development?

A)Enhanced mitochondrial biogenesis
B)Accelerated telomere shortening
C)Increased satellite cell proliferation
D)Suppressed myostatin expression

💡 Explanation

Oxidative stress from intense exercise damages DNA, which leads to accelerated telomere shortening, because telomeres protect chromosomes during replication. This limits cell division capacity and hinders muscle repair and growth; therefore, telomere shortening impairs long-term muscle development, rather than promoting mitochondrial biogenesis or other growth-related processes.

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