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Human Body & Health

In a patient experiencing septic shock and resulting acidosis, which alteration in hemoglobin's behavior within blood is most likely?

A)Increased oxygen affinity at tissues
B)Enhanced 2,3-BPG binding reduction
C)Decreased oxygen affinity at tissues
D)Greater hemoglobin tetramer stability

💡 Explanation

Acidosis, a consequence of septic shock, leads to an increased concentration of H+ ions. This promotes the Bohr effect, causing hemoglobin to release oxygen more readily at the tissues because the affinity of hemoglobin for oxygen decreases. Therefore, decreased oxygen affinity is the outcome, rather than increased affinity.

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