What distinguishes cortical reaction from capacitation during fertilization?

💡 Explanation

The cortical reaction, triggered by sperm-egg fusion, involves the release of cortical granules, altering the zona pellucida and preventing further sperm penetration, because it establishes a block to polyspermy. Therefore, the cortical reaction is key to monospermy, rather than capacitation, which prepares the sperm for fertilization.

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