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Human Body & Health

What happens to bacterial antibiotic resistance when a mutation deactivates a cell's own DNA mismatch repair mechanism?

A)Decreased mutation rate overall
B)Slower adaptation to antibiotics
C)Decreased horizontal gene transfer
D)Accelerated development of resistance alleles

💡 Explanation

If the DNA mismatch repair mechanism fails due to mutation, DNA replication errors accumulate because the repair system is broken; therefore, accelerated antibiotic resistance development is likely, rather than a slower adaptation, a decreased mutation rate, or a drop in gene transfer.

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