Why does kidney stone formation increase significantly when urine pH consistently remains above 7.0?

💡 Explanation

Kidney stone formation increases with elevated urine pH due to increased calcium oxalate crystallization, because a higher pH reduces the solubility of calcium oxalate, making it more likely to precipitate. Therefore, calcium oxalate crystal formation increases, rather than other factors like phosphate solubility, citrate excretion, or uric acid solubility playing the main role.

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