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Which behavior in high-performance liquid chromatography (HPLC) results when the stationary phase’s interaction potential weakens?

A)Increased analyte elution velocity
B)Decreased baseline signal stability
C)Increased stationary phase saturation
D)Decreased mobile phase constant viscosity

💡 Explanation

Increased analyte elution velocity occurs because reduced interaction potential weakens the interaction between the analyte and the stationary phase, impacting retention. As a result, the analyte spends less time interacting and elutes faster, therefore elution velocity increases, rather than changes in viscosity or saturation.

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