Which mechanism explains why prolonged exposure to neonicotinoid pesticides disrupts insect nervous systems at the synaptic level?

💡 Explanation

Neonicotinoids act as agonists of acetylcholine receptors; they bind and persistently activate these receptors, because they are not effectively broken down by acetylcholinesterase. This causes overstimulation and eventual paralysis, therefore persistent receptor activation is the mechanism, rather than degradation or GABA channel modulation.

• Why does bone mineral density reduce more drastically in the femoral neck compared to the lumbar spine under prolonged microgravity conditions?
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