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Human Body & Health

Why does bone remodeling increase around a femoral hip implant after prolonged use, even when initial stress shielding was minimal?

A)Reduced piezoelectric signal generation increases osteoblast activity
B)Enhanced compressive forces directly inhibit osteoclast differentiation
C)Elevated cytokine concentration decreases calcium phosphate absorption
D)Micro-motion stimulates bone turnover exceeding adaptation threshold

💡 Explanation

Increased bone remodeling around a femoral hip implant occurs because micro-motion induces repetitive mechanical signaling at the bone-implant interface, stimulating bone turnover. The adaptive capacity is eventually exceeded. Therefore, the micro-motion drives remodeling, rather than direct stress shielding effects, which might be more prominent earlier.

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