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← ScienceWhich outcome impedes protein folding relying on water?
A)Hydrophobic effect minimizes water contact✓
B)Disulfide bridges promote rigid structures
C)Peptide bonds maximize chain flexibility
D)Salt bridges enhance ionic interactions
💡 Explanation
Protein folding slows when incorrectly hydrated surfaces cluster because the hydrophobic effect excludes water molecules, hindering proper protein conformation. Therefore, non-native aggregation reduces folding efficiency, rather than disulfide bridge formation or peptide / salt bridge strength alterations.
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