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← Nature & AnimalsWhich outcome is caused by disruption of ion channel regulation during arousal from mammalian hibernation?
A)Cardiac arrhythmias from membrane depolarization✓
B)Pulmonary edema from capillary permeability
C)Renal failure from glomerular filtration decline
D)Cerebral hypoxia from vasoconstriction blockade
💡 Explanation
When arousal from hibernation is initiated, altered ion channel regulation causes imbalances in ionic gradients, particularly K+ and Na+, because temperature sensitivity of ion channels changes, leading to erratic cardiac muscle depolarization. Therefore cardiac arrhythmias occur, rather than edema, failure, or hypoxia which involve distinct mechanisms related to fluid dynamics and oxygen transport.
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