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← Human Body & HealthWhich outcome occurs when a patient with chronic kidney disease experiences persistently low mineral availability to bone?
A)Elevated bone mineral density
B)Increased osteoclast activity✓
C)Suppressed PTH secretion
D)Enhanced vitamin D synthesis
💡 Explanation
Increased osteoclast activity occurs because low mineral availability stimulates parathyroid hormone (PTH) secretion, which, in turn, activates osteoclasts to resorb bone and release calcium and phosphate into the bloodstream; therefore, osteoclast activity increases, rather than PTH secretion being suppressed as the body attempts to maintain calcium homeostasis.
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