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Human Body & Health

Which outcome occurs when adaptive immunological pressure overwhelms somatic hypermutation?

A)Escaped B-cell receptor production
B)Excessive regulatory T-cell suppression
C)Prolonged autoimmune antigenic mimicry
D)Unchecked complement system cytotoxicity

💡 Explanation

Escaped B-cell receptor production occurs because cells proliferate without proper selection due to somatic hypermutation being surpassed by replication; therefore, autoreactive escape occurs, rather than robust T-cell regulation under normal load.

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