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Which outcome occurs when inhibiting carbonic anhydrase in red blood cells within systemic capillaries?

A)Reduced carbon dioxide diffusion into cells
B)Decreased bicarbonate ion concentration in plasma
C)Increased oxygen binding affinity to hemoglobin
D)Elevated partial pressure of oxygen in tissues

💡 Explanation

When carbonic anhydrase is inhibited, the reversible reaction between carbon dioxide and water to form carbonic acid is slowed, due to reduced reaction rate. Because the equilibrium shifts against dissolved carbon dioxide diffusion into red blood cells is reduced. Reaching of oxygen hemoglobin curve doesn't reach steady rate, leading to reduced intake of oxygen into the tissues. Therefore, reduced carbon dioxide diffusion results rather than increasing oxygen, bicarbonate ion or raising partial pressures in tissues, which would require promoting the enzyme kinetics

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