Which outcome results when prolonged arterial hypertension causes cardiomyocyte hypertrophy?

💡 Explanation

Persistent hypertension leads to increased afterload and compensatory cardiomyocyte hypertrophy, through the Frank-Starling mechanism leading initially to enhanced contractility and eventually to impaired relaxation and diastolic heart failure; therefore, diastolic dysfunction increases rather than immediate systolic improvements because contractility remains unchanged initially.

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