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← Human Body & HealthWhich process is responsible for hypoglycemia observed during acetaminophen (paracetamol) overdose, impacting liver function?
A)Enhanced hepatic glycogenolysis
B)Increased insulin-mediated glucose uptake
C)Impaired hepatic gluconeogenesis✓
D)Stimulation of bile acid synthesis
💡 Explanation
Impaired gluconeogenesis leads to hypoglycemia in acetaminophen overdose because the liver's ability to synthesize glucose from non-carbohydrate precursors is compromised. Therefore, blood glucose levels fall, rather than glycogenolysis increasing glucose release or bile acid synthesis having a direct impact.
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