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Which risk increases when disulfide bonds break in insulin?

A)Loss of tertiary protein structure
B)Increased peptide hydrophobicity occurs
C)Enhanced receptor binding affinity
D)Elevated glucose production occurs abruptly

💡 Explanation

When disulfide bonds break, it disrupts the forces stabilizing the proteins tertiary configuration because the mechanism is destabilization by unfolding, therefore the protein loses its proper three-dimensional shape and function, rather than becoming more hydrophobic or binding more readily.

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