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← Nature & AnimalsWhich signaling malfunction during metamorphosis leads to malformed adult wings in insect imaginal discs?
A)Downregulation of Hedgehog signaling✓
B)Overexpression of apoptosis inhibitors
C)Increased juvenile hormone production
D)Mutation in cuticle protein synthesis
💡 Explanation
During metamorphosis, accurate wing development relies on Hedgehog signaling regulating cell fate and patterning within imaginal discs; when Hedgehog signaling is downregulated, proper wing venation and shape formation is disrupted. Therefore, diminished Hedgehog signaling leads to malformed wings rather than changes apoptosis, juvenile hormone, or cuticle synthesis which affect other developmental processes.
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