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← Human Body & HealthWhy does a dialysis patient experience increased bone fragility compared to a healthy individual?
A)Decreased erythropoietin stimulates osteoblasts
B)Increased phosphate absorption strengthens bone
C)Reduced calcitriol synthesis impairs mineralization✓
D)Elevated albumin binding promotes calcium deposition
💡 Explanation
Reduced calcitriol synthesis occurs because the kidneys cannot effectively convert vitamin D to its active form. This impaired conversion reduces calcium absorption in the intestines, resulting in decreased calcium availability for bone mineralization. Therefore, reduced calcitriol is the reason, rather than increased phosphate or erythropoietin changes.
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