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Human Body & Health

Why does a mature ovarian follicle secrete increased estrogen during the late follicular phase, rather than continuing at a constant rate?

A)LH receptor downregulation occurs
B)Granulosa cell aromatase activity increases
C)Thecal cells undergo apoptosis rapidly
D)Progesterone receptors become desensitized

💡 Explanation

Increased estrogen occurs because granulosa cells within the follicle develop increased aromatase activity, thus upregulating estrogen synthesis. The increased aromatase activity occurs because of FSH signaling. Therefore, estrogen secretion rises, rather than remaining constant, because of induced enzyme production within the follicle.

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