Why does estradiol production sharply decline after ovulation from the dominant follicle?

💡 Explanation

Estradiol production declines due to luteinization, because the granulosa cells of the dominant follicle transform into luteal cells after ovulation. This process changes their steroidogenic enzyme expression, therefore estradiol synthesis decreases, rather than FSH directly downregulating receptors or inhibin acutely suppressing aromatase.

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